CHRONIC INTRATHECAL CANNULATION ENHANCES NOCICEPTIVE RESPONSES IN RATS

The influence of a chronically implanted spinal cannula on the nociceptive response induced by mechanical, chemical or thermal stimuli was evaluated.The hyperalgesia in response to mechanical stimulation induced by carrageenin or prostaglandin E2 (PGE2) was significantly increased in cannulated (Cn) rats, compared with naive Existalite XCR Combo Un

Burn injuries are an endemic health concern in developing countries.Globally, Africa has the highest incidence of burn injuries per capita.A total of 2.3% of the South African population suffer burn injuries annually and may present at community pharmacies and primary healthcare (PHC) facilities.Pharmacists and PHC nurses must, therefore, remain ab